Increase in plasma endotoxin concentrations and the expression of Toll-like receptors and suppressor of cytokine signaling-3 in mononuclear cells after a high-fat, high-carbohydrate meal: implications for insulin resistance.

Ghanim, Husam; Abuaysheh, Sanaa; Ling Sia, Ching; Korzeniewski, Kelly; Chaudhuri, Ajay; Manuel Fernandez-Real, Jose; Dandona, Paresh

doi:10.2337/dc09-0979

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Increase in plasma endotoxin concentrations and the expression of Toll-like receptors and suppressor of cytokine signaling-3 in mononuclear cells after a high-fat, high-carbohydrate meal: implications for insulin resistance.

Shared by NobleBlocks on Dec 1, 2009 • 12:00 AM UTC

Authors:

Husam Ghanim

Sanaa Abuaysheh

Ching Ling Sia

Abstract

OBJECTIVE: To compare the effect of a high-fat, high-carbohydrate meal (HFHC) with that of a high-fiber and fruit meal on the concentrations of endotoxin (lipopolysaccharide [LPS]), LPS-binding protein (LBP), the expression of toll-like receptors (TLRs), and the suppressor of cytokine signaling-3 (S...

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