Thrombospondin Type-1 Domain-Containing 7A in Idiopathic Membranous Nephropathy

M. Tomas, Nicola; H. Beck, Laurence; Meyer‐Schwesinger, Catherine; Seitz‐Polski, Barbara; Ma, Hong; Zahner, Gunther; Dolla, Guillaume; Hoxha, Elion; Helmchen, Udo; Dabert-Gay, Anne-Sophie; Debayle, Delphine; L. Merchant, Michael; B. Klein, Jon; J. Salant, David; A.K. Stahl, Rolf; Lambeau, Gérard

doi:10.1056/nejmoa1409354

Public

Thrombospondin Type-1 Domain-Containing 7A in Idiopathic Membranous Nephropathy

Published in New England Journal of Medicine • Nov 13, 2014

Authors:

Nicola M. Tomas

Laurence H. Beck

Catherine Meyer‐Schwesinger

Abstract

BACKGROUND: Idiopathic membranous nephropathy is an autoimmune disease. In approximately 70% of patients, it is associated with autoantibodies against the phospholipase A2 receptor 1 (PLA2R1). Antigenic targets in the remaining patients are unknown. METHODS: Using Western blotting, we screened serum...

Subject

Membranous nephropathy

Autoantibody

Medicine

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