Induction of protective CTL responses in newborn mice by a murine retrovirus.

M, Sarzotti; DS, Robbins; PM, Hoffman

doi:10.1126/science.271.5256.1726

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Induction of protective CTL responses in newborn mice by a murine retrovirus.

Shared by NobleBlocks on Mar 1, 1996 • 12:00 AM UTC

Authors:

Sarzotti M

Robbins DS

Hoffman PM

Abstract

The susceptibility of neonates to virus-induced disease is thought to reflect, in part, the immaturity of their immune systems. However, inoculation of newborn mice with low doses of Cas-Br-M murine leukemia virus induced a protective cytotoxic T lymphocyte (CTL) response. The inability of neonates ...

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