Characterization of Reproductive, Metabolic, and Endocrine Features of Polycystic Ovary Syndrome in Female Hyperandrogenic Mouse Models

Sarah Lee Caldwell, Aimée; J. Middleton, Linda; Jimenez, M.; Desai, Reena; C. McMahon, Aisling; M. Allan, Charles; J. Handelsman, David; A. Walters, Kirsty

doi:10.1210/en.2014-1196

Public

Characterization of Reproductive, Metabolic, and Endocrine Features of Polycystic Ovary Syndrome in Female Hyperandrogenic Mouse Models

Published in Endocrinology • May 30, 2014

Authors:

Aimée Sarah Lee Caldwell

Linda J. Middleton

M. Jimenez

Abstract

Polycystic ovary syndrome (PCOS) affects 5-10% of women of reproductive age, causing a range of reproductive, metabolic and endocrine defects including anovulation, infertility, hyperandrogenism, obesity, hyperinsulinism, and an increased risk of type 2 diabetes and cardiovascular disease. Hyperandr...

Subject

Polycystic ovary

Anovulation

Endocrinology

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