Outcome in Hodgkin's Lymphoma Can Be Predicted from the Presence of Accompanying Cytotoxic and Regulatory T Cells

Álvaro, Tomás; Lejeune, Marylène; Teresa Salvadó, Ma; Bosch, Ramón; F. Garcı́a, Juan; Jaén, Joaquín; H. Banham, Alison; Roncador, Giovanna; Montalbán, Carlos; Á. Piris, Miguel

doi:10.1158/1078-0432.ccr-04-1869

Public

Outcome in Hodgkin's Lymphoma Can Be Predicted from the Presence of Accompanying Cytotoxic and Regulatory T Cells

Published in Clinical Cancer Research • Feb 15, 2005

Authors:

Tomás Álvaro

Marylène Lejeune

Ma Teresa Salvadó

Abstract

PURPOSE: Recent studies of Hodgkin's lymphoma (HL) have suggested that the presence of regulatory T cells in the reactive background may explain the inhibition of the antitumoral host immune response observed in these patients. This study aimed to assess the relevance of regulatory T cells and CTLs ...

Subject

FOXP3

Cytotoxic T cell

Lymphoma

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