Integrated mutational and cytogenetic analysis identifies new prognostic subgroups in chronic lymphocytic leukemia

Rossi, Davide; Rasi, Silvia; Spina, Valeria; Bruscaggin, Alessio; Monti, Sara; Ciardullo, Carmela; Deambrogi, Clara; Khiabanian, Hossein; Serra, Roberto; Bertoni, Francesco; Forconi, Francesco; Laurenti, Luca; Marasca, Roberto; Dal Bo, Michele; Maria Rossi, Francesca; Bulian, Pietro; Nomdedéu, Josep; Del Poeta, Giovanni; Gattei, Valter; Pasqualucci, Laura; Rabadán, Raúl; Foà, Robin; Dalla‐Favera, Riccardo; Gaïdano, Gianluca

doi:10.1182/blood-2012-09-458265

Public

Integrated mutational and cytogenetic analysis identifies new prognostic subgroups in chronic lymphocytic leukemia

Published in Blood • Dec 13, 2012

Authors:

Davide Rossi

Silvia Rasi

Valeria Spina

Abstract

The identification of new genetic lesions in chronic lymphocytic leukemia (CLL) prompts a comprehensive and dynamic prognostic algorithm including gene mutations and chromosomal abnormalities and their changes during clonal evolution. By integrating mutational and cytogenetic analysis in 1274 CLL sa...

Subject

Chronic lymphocytic leukemia

Somatic evolution in cancer

Biology

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!