Metabolomic Profiles Are Gender, Disease and Time Specific in the Interleukin-10 Gene-Deficient Mouse Model of Inflammatory Bowel Disease

Tso, Victor; C. Sydora, Beate; Foshaug, Rae; A. Churchill, Thomas; Doyle, Jason; M. Slupsky, Carolyn; N. Fedorak, Richard

doi:10.1371/journal.pone.0067654

Public

Metabolomic Profiles Are Gender, Disease and Time Specific in the Interleukin-10 Gene-Deficient Mouse Model of Inflammatory Bowel Disease

Published in PLoS ONE • Jul 9, 2013

Authors:

Victor Tso

Beate C. Sydora

Rae Foshaug

Abstract

Metabolomic profiling can be used to study disease-induced changes in inflammatory bowel diseases (IBD). The aim of this study was to investigate the difference in the metabolomic profile of males and females as they developed IBD. Using the IL-10 gene-deficient mouse model of IBD and wild-type mice...

Subject

Metabolomics

Inflammatory bowel disease

Disease

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