Dissimilarity in aflatoxin dose-response relationships between DNA adduct formation and development of preneoplastic foci in rat liver

Root, Martin; Lange, Theodore; Colin Campbell, T.

doi:10.1016/s0009-2797(97)00078-1

Public

Dissimilarity in aflatoxin dose-response relationships between DNA adduct formation and development of preneoplastic foci in rat liver

Published in Chemico-Biological Interactions • Oct 1, 1997

Authors:

Martin Root

Theodore Lange

T. Colin Campbell

Abstract

Earlier work in this laboratory and that carried out by others demonstrated that after a single dose of aflatoxin B1 (AFB) the resulting liver AFB-DNA adduct levels were directly proportional to dose. Earlier work also showed that after ten daily doses the AFB dose-response relationship with gamma-g...

Subject

Aflatoxin

DNA

Adduct

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