A Chelator-Free Multifunctional [64Cu]CuS Nanoparticle Platform for Simultaneous Micro-PET/CT Imaging and Photothermal Ablation Therapy

Zhou, Min; Zhang, Rui; Huang, Miao; Lü, Wei; Song, Shaoli; P. Melancon, Marites; Tian, Mei; Liang, Dong; Li, Chun

doi:10.1021/ja106855m

Public

A Chelator-Free Multifunctional [64Cu]CuS Nanoparticle Platform for Simultaneous Micro-PET/CT Imaging and Photothermal Ablation Therapy

Published in Journal of the American Chemical Society • Oct 13, 2010

Authors:

Min Zhou

Rui Zhang

Miao Huang

Abstract

We synthesized and evaluated a novel class of chelator-free [(64)Cu]CuS nanoparticles (NPs) suitable both for PET imaging and as photothermal coupling agents for photothermal ablation. These [(64)Cu]CuS NPs are simple to make, possess excellent stability, and allow robust noninvasive micro-PET imagi...

Subject

Photothermal therapy

Chemistry

Nanoparticle

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