A Polycistronic MicroRNA Cluster, <i>miR-17-92</i> , Is Overexpressed in Human Lung Cancers and Enhances Cell Proliferation

Hayashita, Yoji; Osada, Hirotaka; Tatematsu, Yoshio; Yamada, Hideki; Yanagisawa, Kiyoshi; Tomida, Shuta; Yatabe, Yasushi; Kawahara, Katsunobu; Sekido, Yoshitaka; Takahashi, Takashi

doi:10.1158/0008-5472.can-05-2352

Public

A Polycistronic MicroRNA Cluster, miR-17-92 , Is Overexpressed in Human Lung Cancers and Enhances Cell Proliferation

Published in Cancer Research • Nov 1, 2005

Authors:

Yoji Hayashita

Hirotaka Osada

Yoshio Tatematsu

Abstract

MicroRNAs (miRNAs) are small noncoding RNAs, thought to be involved in physiologic and developmental processes by negatively regulating expression of target genes. We have previously reported frequent down-regulation of the let-7 miRNA family in lung cancers and, in the present study, assessed alter...

Subject

microRNA

Biology

Lung cancer

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