The outcome of full-intensity and reduced-intensity conditioning matched sibling or unrelated donor transplantation in adults with Philadelphia chromosome–negative acute lymphoblastic leukemia in first and second complete remission

I. Marks, David; Wang, Tao; S. Pérez, Waleska; H. Antin, Joseph; A. Copelan, Edward; Peter Gale, Robert; George, Biju; Gupta, Vikas; Halter, Joerg; Jean Khoury, H.; R. Klumpp, Thomas; M. Lazarus, Hillard; Lewis, Victor; L. McCarthy, Philip; A. Rizzieri, David; Sabloff, Mitchell; Szer, Jeff; S. Tallman, Martin; J. Weisdorf, Daniel

doi:10.1182/blood-2010-01-264077

Public

The outcome of full-intensity and reduced-intensity conditioning matched sibling or unrelated donor transplantation in adults with Philadelphia chromosome–negative acute lymphoblastic leukemia in first and second complete remission

Published in Blood • Apr 20, 2010

Authors:

David I. Marks

Tao Wang

Waleska S. Pérez

Abstract

We examined the efficacy of reduced-intensity conditioning (RIC) and compared outcomes of 93 patients older than 16 years after RIC with 1428 patients receiving full-intensity conditioning for allografts using sibling and unrelated donors for Philadelphia-negative acute lymphoblastic leukemia (ALL) ...

Subject

Medicine

Melphalan

Conditioning

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