Intracellular Signaling by Hydrolysis of Phospholipids and Activation of Protein Kinase C

Hydrolysis of inositol phospholipids by phospholipase C is initiated by either receptor stimulation or opening of Ca2+ channels. This was once thought to be the sole mechanism to produce the diacylglycerol that links extracellular signals to intracellular events through activation of protein kinase ... View More