Involvement of increased excitatory amino acids and intracellular Ca2+ concentration in the spinal dorsal horn in an animal model of neuropathic pain

Kawamata, Mikito; Omote, Keiichi

doi:10.1016/s0304-3959(96)03222-8

Public

Involvement of increased excitatory amino acids and intracellular Ca2+ concentration in the spinal dorsal horn in an animal model of neuropathic pain

Published in Pain • Nov 1, 1996

Authors:

Mikito Kawamata

Keiichi Omote

Abstract

Neuropathic pain following nerve injury is believed to involve excitatory amino acids (EAAs) and Ca2+-mediated neuronal plastic changes in the central nervous system (CNS). This study was designed to investigate the changes in glutamate and aspartate contents in the dorsal half of the spinal cord fo...

Subject

Neuropathic pain

Sciatic nerve

Spinal cord

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