Comparison of the Mechanism of Toxicity of Zinc Oxide and Cerium Oxide Nanoparticles Based on Dissolution and Oxidative Stress Properties

Xia, Tian; Kovochich, Michael; Liong, Monty; Mädler, Lutz; Gilbert, Benjamin; Shi, Haibin; I. Yeh, Joanne; I. Zink, Jeffrey; E. Nel, André

doi:10.1021/nn800511k

Public

Comparison of the Mechanism of Toxicity of Zinc Oxide and Cerium Oxide Nanoparticles Based on Dissolution and Oxidative Stress Properties

Published in ACS Nano • Oct 1, 2008

Authors:

Tian Xia

Michael Kovochich

Monty Liong

Abstract

Nanomaterials (NM) exhibit novel physicochemical properties that determine their interaction with biological substrates and processes. Three metal oxide nanoparticles that are currently being produced in high tonnage, TiO(2), ZnO, and CeO(2), were synthesized by flame spray pyrolysis process and com...

Subject

Oxidative stress

Reactive oxygen species

Cytotoxicity

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