Association of circulating TNF-α and IL-6 with ageing and parkinsonism

John Dobbs, R.; Charlett, André; G. Purkiss, Andrew; M. Dobbs, Sylvia; Weller, Clive; Peterson, D.W.

doi:10.1111/j.1600-0404.1999.tb00721.x

Public

Association of circulating TNF-α and IL-6 with ageing and parkinsonism

Published in Acta Neurologica Scandinavica • Jul 1, 1999

Authors:

R. John Dobbs

André Charlett

Andrew G. Purkiss

Abstract

INTRODUCTION: We propose that the increase in TNF-alpha and IL-6 in the brain in idiopathic parkinsonism is in response to a peripheral immune/ inflammatory process, so ubiquitous as to be responsible for the resemblance between ageing and parkinsonism. METHODS: Circulating cytokine was measured in ...

Subject

Parkinsonism

Ageing

Association (psychology)

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