Size‐ and shape‐dependent pleural translocation, deposition, fibrogenesis, and mesothelial proliferation by multiwalled carbon nanotubes

Xu, Jiegou; B. Alexander, David; Futakuchi, Mitsuru; Numano, Takamasa; Fukamachi, Katsumi; Suzui, Masumi; Omori, Toyonori; Kanno, Jun; Hirose, Akihiko; Tsuda, Hiroyuki

doi:10.1111/cas.12437

Public

Size‐ and shape‐dependent pleural translocation, deposition, fibrogenesis, and mesothelial proliferation by multiwalled carbon nanotubes

Published in Cancer Science • May 11, 2014

Authors:

Jiegou Xu

David B. Alexander

Mitsuru Futakuchi

Abstract

Multiwalled carbon nanotubes (MWCNT) have a fibrous structure similar to asbestos, raising concern that MWCNT exposure may lead to asbestos-like diseases. Previously we showed that MWCNT translocated from the lung alveoli into the pleural cavity and caused mesothelial proliferation and fibrosis in t...

Subject

Mesothelial Cell

Fibrosis

Lung

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