Suppressive Effect of Natural Sesquiterpenoids on Inducible Cyclooxygenase (COX-2) and Nitric Oxide Synthase (iNOS) Activity in Mouse Macrophage Cells

Kook Lee, Sang; Hong, Chai-Hee; Huh, Sun-Kyung; Kim, Sun-Sook; Oh, O-Jin; Min, Hye‐Young; Park, Kwang-Kyun; Chung, Won‐Yoon; Hwang, Jae‐Kwan

doi:10.1615/jenvironpatholtoxicoloncol.v21.i2.70

Public

Suppressive Effect of Natural Sesquiterpenoids on Inducible Cyclooxygenase (COX-2) and Nitric Oxide Synthase (iNOS) Activity in Mouse Macrophage Cells

Published in Journal of Environmental Pathology Toxicology and Oncology • Jan 1, 2002

Authors:

Sang Kook Lee

Chai-Hee Hong

Sun-Kyung Huh

Abstract

Prostaglandins and nitric oxide produced by inducible cyclooygenase (COX-2) and nitric oxide synthase (iNOS), respectively, have been implicated as important mediators in the processes of inflammation and carcinogenesis. These potential COX-2 and iNOS inhibitors have been considered as antiinflammat...

Subject

Nitric oxide synthase

Cyclooxygenase

Nitric oxide

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