Early cyclosporine withdrawal from a sirolimus-based regimen results in better renal allograft survival and renal function at 48 months after transplantation.

R, Oberbauer; G, Segoloni; JM, Campistol; H, Kreis; A, Mota; J, Lawen; G, Russ; JM, Grinyó; G, Stallone; A, Hartmann; JR, Pinto; J, Chapman; JT, Burke; Y, Brault; JF, Neylan

doi:10.1111/j.1432-2277.2004.00052.x

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Early cyclosporine withdrawal from a sirolimus-based regimen results in better renal allograft survival and renal function at 48 months after transplantation.

Shared by NobleBlocks on Jan 1, 2005 • 12:00 AM UTC

Authors:

Oberbauer R

Segoloni G

Campistol JM

Abstract

We report the 48-month results of a trial testing whether withdrawal of cyclosporine (CsA) from a sirolimus (SRL)-CsA-steroid (ST) regimen would impact renal allograft survival. Eligible patients receiving SRL-CsA-ST from transplantation were randomly assigned at 3 months to remain on triple therapy...

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