Chemoimmunotherapy for hemophagocytic lymphohistiocytosis: long-term results of the HLH-94 treatment protocol

Trottestam, Helena; Horne, AnnaCarin; Aricò, Maurizio; Maarten Egeler, R.; H. Filipovich, Alexandra; Gadner, Helmut; Imashuku, Shinsaku; Ladisch, Stephan; Webb, David; Janka, Gritta; Henter, Jan-Inge; the Histiocyte Society, for

doi:10.1182/blood-2011-06-356261

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Chemoimmunotherapy for hemophagocytic lymphohistiocytosis: long-term results of the HLH-94 treatment protocol

Shared by NobleBlocks on Oct 27, 2011 • 12:00 AM UTC

Authors:

Helena Trottestam

AnnaCarin Horne

Maurizio Aricò

Abstract

Abstract Hemophagocytic lymphohistiocytosis (HLH) used to have a dismal prognosis. We report the final results of HLH-94, the largest prospective diagnostic/therapeutic HLH study so far. The treatment includes immunosuppressive and cytotoxic therapy aiming at clinical remission, followed by HSCT in ...

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