Randomized Phase II Study of Neoadjuvant Combined-Modality Chemoradiation for Distal Rectal Cancer: Radiation Therapy Oncology Group Trial 0012

Mohiuddin, Mohammed; Winter, Kathryn; P. Mitchell, Edith; Hanna, Nader; Yuen, Albert; W. Nichols, Charles; Shane, Robert; J. Hayostek, Cherie; G. Willett, Christopher

doi:10.1200/jco.2005.03.6095

Public

Randomized Phase II Study of Neoadjuvant Combined-Modality Chemoradiation for Distal Rectal Cancer: Radiation Therapy Oncology Group Trial 0012

Published in Journal of Clinical Oncology • Jan 31, 2006

Authors:

Mohammed Mohiuddin

Kathryn Winter

Edith P. Mitchell

Abstract

PURPOSE: To evaluate the rate of pathologic complete response and toxicity of neoadjuvant chemoradiation for advanced T3/T4 distal rectal cancers in a randomized phase II study PATIENTS AND METHODS: Patients with clinical T3/T4 distal rectal cancers were randomly assigned in a phase II study to rece...

Subject

Medicine

Colorectal cancer

Radiation therapy

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