Clinical trial: lubiprostone in patients with constipation‐associated irritable bowel syndrome – results of two randomized, placebo‐controlled studies

A. Drossman, Douglas; D. Chey, William; F. Johanson, John; Fass, Ronnie; Scott, Charles; M. Panas, Raymond; Ueno, Ryuji

doi:10.1111/j.1365-2036.2008.03881.x

Public

Clinical trial: lubiprostone in patients with constipation‐associated irritable bowel syndrome – results of two randomized, placebo‐controlled studies

Published in Alimentary Pharmacology & Therapeutics • Nov 4, 2008

Authors:

Douglas A. Drossman

William D. Chey

John F. Johanson

Abstract

BACKGROUND: Effective treatments for irritable bowel syndrome with constipation (IBS-C) are lacking. AIM: To assess the efficacy and safety of lubiprostone in IBS-C. METHODS: A combined analysis was performed among 1171 patients with a Rome II diagnosis of IBS-C in two phase-3 randomized trials of l...

Subject

Lubiprostone

Medicine

Placebo

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