Mesenchymal stem cells inhibit the formation of cytotoxic T lymphocytes, but not activated cytotoxic T lymphocytes or natural killer cells

Rasmusson, Ida; Ringdén, Olle; Sundberg, Berit; Le Blanc, Katarina

doi:10.1097/01.tp.0000082540.43730.80

Public

Mesenchymal stem cells inhibit the formation of cytotoxic T lymphocytes, but not activated cytotoxic T lymphocytes or natural killer cells

Published in Transplantation • Oct 27, 2003

Authors:

Ida Rasmusson

Olle Ringdén

Berit Sundberg

Abstract

BACKGROUND: Mesenchymal stem cells (MSCs) can reduce the incidence of graft-versus-host disease because of their ability to inhibit T-lymphocyte proliferation. There are no publications on the effect that MSCs have on cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells, effector cells vital...

Subject

Cytotoxic T cell

Mesenchymal stem cell

Lymphokine-activated killer cell

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