Synthesis, characterization, and bioconjugation of fluorescent gold nanoclusters toward biological labeling applications.

CA, Lin; TY, Yang; CH, Lee; SH, Huang; RA, Sperling; M, Zanella; JK, Li; JL, Shen; HH, Wang; HI, Yeh; WJ, Parak; WH, Chang; WH, Chang

doi:10.1021/nn800632j

Public

Synthesis, characterization, and bioconjugation of fluorescent gold nanoclusters toward biological labeling applications.

Shared by NobleBlocks on Feb 1, 2009 • 12:00 AM UTC

Authors:

Lin CA

Yang TY

Lee CH

Abstract

Synthesis of ultrasmall water-soluble fluorescent gold nanoclusters is reported. The clusters have a decent quantum yield, high colloidal stability, and can be readily conjugated with biological molecules. Specific staining of cells and nonspecific uptake by living cells is demonstrated.

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