Mesenchymal Stem Cells: Mechanisms of Immunomodulation and Homing

Yagi, Hiroshi; Soto–Gutiérrez, Alejandro; Parekkadan, Biju; Kitagawa, Yuko; G. Tompkins, Ronald; Kobayashi, Naoya; L. Yarmush, Martin

doi:10.3727/096368910x508762

Public

Mesenchymal Stem Cells: Mechanisms of Immunomodulation and Homing

Published in Cell Transplantation • Jun 1, 2010

Authors:

Hiroshi Yagi

Alejandro Soto–Gutiérrez

Biju Parekkadan

Abstract

Mesenchymal stem cell (MSC) transplantation has been explored as a new clinical approach to repair injured tissue. A growing corpus of studies have highlighted two important aspects of MSC therapy: 1) MSCs can modulate T-cell-mediated immunological responses, and (2) systemically administered MSCs h...

Subject

Homing (biology)

Mesenchymal stem cell

Immune system

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