Autoantibodies and microvascular damage are independent predictive factors for the progression of Raynaud's phenomenon to systemic sclerosis: A twenty‐year prospective study of 586 patients, with validation of proposed criteria for early systemic sclerosis

Koenig, Martial; Joyal, France; J. Fritzler, Marvin; Roussin, André; Abrahamowicz, Michal; Boire, Gilles; Goulet, Jean‐Richard; Rich, Éric; Grodzicky, Tamara; Raymond, Yves; Senécal, Jean‐Luc

doi:10.1002/art.24038

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Autoantibodies and microvascular damage are independent predictive factors for the progression of Raynaud's phenomenon to systemic sclerosis: A twenty‐year prospective study of 586 patients, with validation of proposed criteria for early systemic sclerosis

Shared by NobleBlocks on Nov 26, 2008 • 12:00 AM UTC

Authors:

Martial Koenig

France Joyal

Marvin J. Fritzler

Abstract

Abstract Objective To identify in patients with Raynaud's phenomenon (RP) independent markers that predict progression to definite systemic sclerosis (SSc) and to determine in patients with progression to SSc the type and sequence of microvascular damage and its relationship to SSc‐specific autoanti...

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