Haplotypes of CYP3A4 and their close linkage with CYP3A5 haplotypes in a Japanese population.

H, Fukushima-Uesaka; Y, Saito; H, Watanabe; K, Shiseki; M, Saeki; T, Nakamura; K, Kurose; K, Sai; K, Komamura; K, Ueno; S, Kamakura; M, Kitakaze; S, Hanai; T, Nakajima; K, Matsumoto; H, Saito; Y, Goto; H, Kimura; M, Katoh; K, Sugai; N, Minami; K, Shirao; T, Tamura; N, Yamamoto; H, Minami; A, Ohtsu; T, Yoshida; N, Saijo; Y, Kitamura; N, Kamatani; S, Ozawa; J, Sawada

doi:10.1002/humu.9210

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Haplotypes of CYP3A4 and their close linkage with CYP3A5 haplotypes in a Japanese population.

Shared by NobleBlocks on Jan 1, 2004 • 12:00 AM UTC

Authors:

Fukushima-Uesaka H

Saito Y

Watanabe H

Abstract

In order to identify single nucleotide polymorphisms (SNPs) and haplotype frequencies of CYP3A4 in a Japanese population, the distal enhancer and proximal promoter regions, all exons, and the surrounding introns were sequenced from genomic DNA of 416 Japanese subjects. We found 24 SNPs, including 17...

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