Revisiting the ultra-high dose rate effect: implications for charged particle radiotherapy using protons and light ions

Wilson, Puthenparampil; Jones, Bleddyn; Yokoi, T.; A. Hill, Mark; Vojnovic, Borivoj

doi:10.1259/bjr/17827549

Public

Revisiting the ultra-high dose rate effect: implications for charged particle radiotherapy using protons and light ions

Published in British Journal of Radiology • Apr 12, 2012

Authors:

Puthenparampil Wilson

Bleddyn Jones

T. Yokoi

Abstract

OBJECTIVE: To reinvestigate ultra-high dose rate radiation (UHDRR) radiobiology and consider potential implications for hadrontherapy. METHODS: A literature search of cellular UHDRR exposures was performed. Standard oxygen diffusion equations were used to estimate the time taken to replace UHDRR-rel...

Subject

Oxygen enhancement ratio

Irradiation

Oxygen

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