Proof of Single-Molecule Sensitivity in Surface Enhanced Raman Scattering (SERS) by Means of a Two-Analyte Technique

C. Le Ru, Eric; Meyer, Matthias; Etchegoin, P.

doi:10.1021/jp054732v

Public

Proof of Single-Molecule Sensitivity in Surface Enhanced Raman Scattering (SERS) by Means of a Two-Analyte Technique

Published in The Journal of Physical Chemistry B • Jan 10, 2006

Authors:

Eric C. Le Ru

Matthias Meyer

P. Etchegoin

Abstract

A method is proposed to pin down unambiguous proof for single-molecule sensitivity in surface enhanced Raman spectroscopy (SERS). The simultaneous use of two analyte molecules enables a clear confirmation of the single (or few)-molecule nature of the signals. This method eliminates most of the uncer...

Subject

Analyte

Molecule

Raman scattering

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