Inhaled Iloprost for Severe Pulmonary Hypertension

Olschewski, Horst; Simonneau, Gérald; Galiè, Nazzareno; W. Higenbottam, T.; Naeije, Robert; J. Rubin, Lewis; Nikkho, Sylvia; Speich, Rudolf; M. Hoeper, Marius; Behr, Jürgen; Winkler, Jörg; Sitbon, Olivier; Popov, Wladimir; Ardeschir Ghofrani, Hossein; Manes, Alessandra; G. Kiely, David; Ewert, R; Meyer, Andreas; A. Corris, Paul; Delcroix, Marion; Ángel Gómez‐Sánchez, Miguel; Siedentop, Harald; Seeger, Werner

doi:10.1056/nejmoa020204

Public

Inhaled Iloprost for Severe Pulmonary Hypertension

Published in New England Journal of Medicine • Aug 1, 2002

Authors:

Horst Olschewski

Gérald Simonneau

Nazzareno Galiè

Abstract

BACKGROUND: Uncontrolled studies suggested that aerosolized iloprost, a stable analogue of prostacyclin, causes selective pulmonary vasodilatation and improves hemodynamics and exercise capacity in patients with pulmonary hypertension. METHODS: We compared repeated daily inhalations of 2.5 or 5.0 mi...

Subject

Iloprost

Medicine

Pulmonary hypertension

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