Site-restricted persistent cytomegalovirus infection after selective long-term depletion of CD4+ T lymphocytes.

We have established a murine model system for exploring the ability of a CD4 subset-deficient host to cope with cytomegalovirus infection, and reported three findings. First, an antiviral response of the CD8 subset of T lymphocytes could be not only initiated but also maintained for a long period of... View More