Utilization of Magnetic-Activated Cell Sorting and High-Density Single Nucleotide Polymorphism Microarrays Improves Diagnostic Yield and Prognostic Value in Clinical Testing for Patients with Multiple Myeloma and Normal Routine Chromosome Study

Christensen, Todd; Deng, Weiwen; McMahill, Bonnie; Schappert, Joseph; Liu, Weihua; Saleki, Reza; Zou, Ying

doi:10.1159/000361074

Public

Utilization of Magnetic-Activated Cell Sorting and High-Density Single Nucleotide Polymorphism Microarrays Improves Diagnostic Yield and Prognostic Value in Clinical Testing for Patients with Multiple Myeloma and Normal Routine Chromosome Study

Published in Acta Haematologica • Jan 1, 2014

Authors:

Todd Christensen

Weiwen Deng

Bonnie McMahill

Abstract

Multiple myeloma (MM) is a clonal plasma cell disorder. Chromosome and FISH studies are used to provide prognostic information that is useful for refining risk stratification and therapeutic response [1]. Frequently, chromosome study is limited by the inability of plasma cells to proliferate in vitr...

Subject

Single-nucleotide polymorphism

Multiple myeloma

Biology

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