Temperature-Responsive Chromatography Using Poly(<i>N</i>-isopropylacrylamide)-Modified Silica

Kanazawa, Hideko; Yamamoto, Kazuo; Matsushima, Yoshikazu; Takai, Nobuharù; Kikuchi, Akihiko; Sakurai, Yasuhisa; Okano, Teruo

doi:10.1021/ac950359j

Public

Temperature-Responsive Chromatography Using Poly(N-isopropylacrylamide)-Modified Silica

Published in Analytical Chemistry • Jan 1, 1996

Authors:

Hideko Kanazawa

Kazuo Yamamoto

Yoshikazu Matsushima

Abstract

A new concept in chromatography is proposed that utilizes a temperature-responsive surface with a constant aqueous mobile phase. The surface of the silica stationary phase in high-performance liquid chromatography (HPLC) has been modified with temperature-responsive polymers to exhibit temperature-c...

Subject

Chemistry

Poly(N-isopropylacrylamide)

Chromatography

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