Bioavailability of melatonin in humans after day-time administration of D7 melatonin

B. Fourtillan, J.; Brisson, A.M.; Gobin, P.; Ingrand, Isabelle; Decourt, J; Girault, J.

doi:10.1002/1099-081x(200001)21:1<15::aid-bdd215>3.0.co;2-h

Public

Bioavailability of melatonin in humans after day-time administration of D7 melatonin

Published in Biopharmaceutics & Drug Disposition • Oct 13, 2000

Authors:

J. B. Fourtillan

A.M. Brisson

P. Gobin

Abstract

Absolute bioavailability of the neurohormone melatonin (MLT) was studied in 12 young healthy volunteers (six males, six females) after administration at midday, on two separate occasions, of 23 microg by intravenous (i.v.) infusion and 250 microg by oral solution of D(7) MLT, a molecule in which sev...

Subject

Bioavailability

Cmax

Pharmacokinetics

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