Fetal Mesenchymal Stem-Cell Engraftment in Bone after In Utero Transplantation in a Patient with Severe Osteogenesis Imperfecta

Le Blanc, Katarina; Götherström, Cecilia; Ringdén, Olle; Hassan, Moustapha; P. McMahon, Robert; M. Horwitz, Edwin; Annerén, Göran; Axelssön, Ove; Nunn, Janice; Ewald, Uwe; Nordén‐Lindeberg, Solveig; Jansson, Monika; Dalton, Ann; Åström, Eva; Westgren, Magnus

doi:10.1097/01.tp.0000159029.48678.93

Public

Fetal Mesenchymal Stem-Cell Engraftment in Bone after In Utero Transplantation in a Patient with Severe Osteogenesis Imperfecta

Published in Transplantation • May 23, 2005

Authors:

Katarina Le Blanc

Cecilia Götherström

Olle Ringdén

Abstract

BACKGROUND: Mesenchymal stem cells (MSC) are progenitors of mesenchymal tissues such as bone, cartilage, and adipose. Adult human leukocyte antigen (HLA)-matched MSC have been used in cellular therapies of bone disorders such as osteogenesis imperfecta, with promising results. METHODS: A female fetu...

Subject

Osteogenesis imperfecta

Mesenchymal stem cell

Medicine

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