Regulation of Renal Organic Anion Transporter 3 (SLC22A8) Expression and Function by the Integrity of Lipid Raft Domains and their Associated Cytoskeleton

Srimaroeng, Chutima; Perry Cecile, Jennifer; Walden, Ramsey; B. Pritchard, John

doi:10.1159/000350077

Public

Regulation of Renal Organic Anion Transporter 3 (SLC22A8) Expression and Function by the Integrity of Lipid Raft Domains and their Associated Cytoskeleton

Published in Cellular Physiology and Biochemistry • Jan 1, 2013

Authors:

Chutima Srimaroeng

Jennifer Perry Cecile

Ramsey Walden

Abstract

BACKGROUND/AIMS: In humans and rodents, organic anion transporter 3 (Oat3) is highly expressed on the basolateral membrane of renal proximal tubules and mediates the secretion of exogenous and endogenous anions. Regulation of Oat3 expression and function has been observed in both expression system a...

Subject

Organic anion transporter 1

Cell biology

HEK 293 cells

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