Polysaccharide Conjugate Vaccine against Pneumococcal Pneumonia in Adults

J. M. Bonten, Marc; M. Huijts, Susanne; Bolkenbaas, Marieke; Webber, Chris; D. Patterson, Scott; Gault, Samantha; H. van Werkhoven, Cornelis; M.M. van Deursen, Anna; A. M. Sanders, Elisabeth; Verheij, Theo; A. Patton, Michael; McDonough, Anne; Moradoghli-Haftvani, Anita; Smith, Helen; Mellelieu, Tracey; W. Pride, Michael; Crowther, Graham; Schmöele-Thoma, Beate; A. Scott, Daniel; U. Jansen, Kathrin; Lobatto, Rita; J. Oosterman, Bas; L. Visser, Nils; Caspers, Esther; Smorenburg, Andre; A. Emini, Emilio; C. Gruber, William; E. Grobbee, Diederick

doi:10.1056/nejmoa1408544

Public

Polysaccharide Conjugate Vaccine against Pneumococcal Pneumonia in Adults

Published in New England Journal of Medicine • Mar 18, 2015

Authors:

Marc J. M. Bonten

Susanne M. Huijts

Marieke Bolkenbaas

Abstract

BACKGROUND: Pneumococcal polysaccharide conjugate vaccines prevent pneumococcal disease in infants, but their efficacy against pneumococcal community-acquired pneumonia in adults 65 years of age or older is unknown. METHODS: In a randomized, double-blind, placebo-controlled trial involving 84,496 ad...

Subject

Medicine

Community-acquired pneumonia

Pneumonia

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