Gadolinium chelate coated gold nanoparticles as contrast agents for both X-ray computed tomography and magnetic resonance imaging.

C, Alric; J, Taleb; Duc G, Le; C, Mandon; C, Billotey; Meur-Herland A, Le; T, Brochard; F, Vocanson; M, Janier; P, Perriat; S, Roux; O, Tillement

doi:10.1021/ja078176p

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Gadolinium chelate coated gold nanoparticles as contrast agents for both X-ray computed tomography and magnetic resonance imaging.

Shared by NobleBlocks on Apr 12, 2008 • 12:00 AM UTC

Authors:

Alric C

Taleb J

Le Duc G

Abstract

Functionalized gold nanoparticles were applied as contrast agents for both in vivo X-ray and magnetic resonance imaging. These particles were obtained by encapsulating gold cores within a multilayered organic shell which is composed of gadolinium chelates bound to each other through disulfide bonds....

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