Gadolinium Chelate Coated Gold Nanoparticles As Contrast Agents for Both X-ray Computed Tomography and Magnetic Resonance Imaging

Alric, Christophe; Taleb, Jacqueline; Le Duc, Géraldine; A. Mandon, Céline; Billotey, Claire; Le Meur-Herland, Alice; Brochard, Thierry; Vocanson, Francis; Janier, M.; Perriat, Pascal; Roux, Stéphane; Tillement, Olivier

doi:10.1021/ja078176p

Public

Gadolinium Chelate Coated Gold Nanoparticles As Contrast Agents for Both X-ray Computed Tomography and Magnetic Resonance Imaging

Published in Journal of the American Chemical Society • Apr 12, 2008

Authors:

Christophe Alric

Jacqueline Taleb

Géraldine Le Duc

Abstract

Functionalized gold nanoparticles were applied as contrast agents for both in vivo X-ray and magnetic resonance imaging. These particles were obtained by encapsulating gold cores within a multilayered organic shell which is composed of gadolinium chelates bound to each other through disulfide bonds....

Subject

Gadolinium

Chemistry

Magnetic resonance imaging

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