The low density lipoprotein receptor is not required for normal catabolism of Lp(a) in humans.

J. Rader, Daniel; Alexander Mann, W.; J. Cain, William; Kraft, H.G.; Usher, David; A. Zech, Loren; M Hoeg, J; Davignon, Jean; J Lupien, P; Grossman, Mariann

doi:10.1172/jci117794

Public

The low density lipoprotein receptor is not required for normal catabolism of Lp(a) in humans.

Published in Journal of Clinical Investigation • Mar 1, 1995

Authors:

Daniel J. Rader

W. Alexander Mann

William J. Cain

Abstract

Lipoprotein(a) [Lp(a)] is an atherogenic lipoprotein which is similar in structure to low density lipoproteins (LDL). The role of the LDL receptor in the catabolism of Lp(a) has been controversial. We therefore investigated the in vivo catabolism of Lp(a) and LDL in five unrelated patients with homo...

Subject

Catabolism

LDL receptor

Internal medicine

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