Reduced uptake of oxidized low density lipoproteins in monocyte-derived macrophages from CD36-deficient subjects.

Nozaki, Satoshi; Kashiwagi, Hirokazu; Yamashita, Shizuya; Nakagawa, Tsutomu; Kostner, B; Tomiyama, Yoshiaki; Nakata, Atsuyuki; Ishigami, Masato; Miyagawa, Jun-ichiro; Kameda-Takemura, Kaoru

doi:10.1172/jci118231

Public

Reduced uptake of oxidized low density lipoproteins in monocyte-derived macrophages from CD36-deficient subjects.

Published in Journal of Clinical Investigation • Oct 1, 1995

Authors:

Satoshi Nozaki

Hirokazu Kashiwagi

Shizuya Yamashita

Abstract

To clarify the physiological roles of CD36 as an oxidized low density lipoprotein (OxLDL) receptor, we analyzed the monocyte-derived macrophages from normal and two CD36-deficient subjects, since we identified the molecular abnormalities (Kashiwagi, H., Y. Tomiyama, Y. Kosugi, M. Shiraga, R. H. Lips...

Subject

CD36

Receptor

Scatchard plot

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