Increased Plasma Endothelin-1 in Pulmonary Hypertension: Marker or Mediator of Disease?

Stewart, DJ; D. Levy, Robert; Černáček, Peter; Langleben, David

doi:10.7326/0003-4819-114-6-464

Public

Increased Plasma Endothelin-1 in Pulmonary Hypertension: Marker or Mediator of Disease?

Published in Annals of Internal Medicine • Mar 15, 1991

Authors:

DJ Stewart

Robert D. Levy

Peter Černáček

Abstract

OBJECTIVE: To explore the role of endothelin-1, a potent endothelial-derived vasoconstrictor peptide, in pulmonary hypertension, by measuring its concentration in arterial and venous plasma. DESIGN: A survey, case series study. SETTING: University-affiliated hospitals and outpatient clinics. PATIENT...

Subject

Medicine

Mediator

Pulmonary hypertension

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