Increased plasma endothelin-1 in pulmonary hypertension: marker or mediator of disease?

J Stewart, D; D Levy, R; Cernacek, P; Langleben, D

doi:10.7326/0003-4819-114-6-464

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Increased plasma endothelin-1 in pulmonary hypertension: marker or mediator of disease?

Shared by NobleBlocks on Mar 15, 1991 • 12:00 AM UTC

Authors:

D J Stewart

R D Levy

P Cernacek

Abstract

OBJECTIVE: To explore the role of endothelin-1, a potent endothelial-derived vasoconstrictor peptide, in pulmonary hypertension, by measuring its concentration in arterial and venous plasma. DESIGN: A survey, case series study. SETTING: University-affiliated hospitals and outpatient clinics. PATIENT...

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