Endogenous Antimicrobial Peptides and Skin Infections in Atopic Dermatitis

Y. Ong, Peck; Ohtake, Takaaki; Brandt, Corinne; Strickland, Ian; Boguniewicz, Mark; Ganz, Tomas; L. Gallo, Richard; Y.M. Leung, Donald

doi:10.1056/nejmoa021481

Public

Endogenous Antimicrobial Peptides and Skin Infections in Atopic Dermatitis

Published in New England Journal of Medicine • Oct 9, 2002

Authors:

Peck Y. Ong

Takaaki Ohtake

Corinne Brandt

Abstract

BACKGROUND: The innate immune system of human skin contains antimicrobial peptides known as cathelicidins (LL-37) and beta-defensins. In normal skin these peptides are negligible, but they accumulate in skin affected by inflammatory diseases such as psoriasis. We compared the levels of expression of...

Subject

Atopic dermatitis

Antimicrobial peptides

Psoriasis

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!