Role of Capsaicin-Sensitive Afferents in Fever and Cytokine Responses during Systemic and Local Inflammation in Rats

V. Gourine, Alexander; Rudolph, Karin; Korsak, Alla; Kubatko, Justin; Tesfaigzi, Johannes; Kozak, Wiesław; J. Kluger, Matthew

doi:10.1159/000049003

Public

Role of Capsaicin-Sensitive Afferents in Fever and Cytokine Responses during Systemic and Local Inflammation in Rats

Published in NeuroImmunoModulation • Jan 1, 2001

Authors:

Alexander V. Gourine

Karin Rudolph

Alla Korsak

Abstract

OBJECTIVE: Peripheral afferents play an important role in fever. In the present study, we investigated the role of capsaicin-sensitive afferents in fever and cytokine responses during systemic (induced by intraperitoneal lipopolysaccharide, LPS) and local (induced by injection of Freund's incomplete...

Subject

Capsaicin

Tumor necrosis factor alpha

Lipopolysaccharide

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