Fast and Reversible Stimulation of Astrocytic Glycolysis by K<sup>+</sup>and a Delayed and Persistent Effect of Glutamate

X. Bittner, Carla; Valdebenito, Rocío; Ruminot, Iván; Loaiza, Anitsi; Larenas, Valeria; Sotelo-Hitschfeld, Tamara; Moldenhauer, Hans; San Martín, Alejandro; Gutiérrez, Robin; Zambrano, Marilyn; Felipe Barros, L.

doi:10.1523/jneurosci.5311-10.2011

Public

Fast and Reversible Stimulation of Astrocytic Glycolysis by K+and a Delayed and Persistent Effect of Glutamate

Published in Journal of Neuroscience • Mar 23, 2011

Authors:

Carla X. Bittner

Rocío Valdebenito

Iván Ruminot

Abstract

Synaptic activity is followed within seconds by a local surge in lactate concentration, a phenomenon that underlies functional magnetic resonance imaging and whose causal mechanisms are unclear, partly because of the limited spatiotemporal resolution of standard measurement techniques. Using a novel...

Subject

Glutamate receptor

Glycolysis

Stimulation

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