Plasma Phospholipid Metabolic Profiling and Biomarkers of Type 2 Diabetes Mellitus Based on High-Performance Liquid Chromatography/Electrospray Mass Spectrometry and Multivariate Statistical Analysis

Wang, Chang; Kong, Hongwei; Guan, Yufeng; Yang, Jun; Gu, Jianren; Yang, Shengli; Xu, Guowang

doi:10.1021/ac0481001

Public

Plasma Phospholipid Metabolic Profiling and Biomarkers of Type 2 Diabetes Mellitus Based on High-Performance Liquid Chromatography/Electrospray Mass Spectrometry and Multivariate Statistical Analysis

Published in Analytical Chemistry • May 17, 2005

Authors:

Chang Wang

Hongwei Kong

Yufeng Guan

Abstract

Liquid chromatography/mass spectrometry (LC/MS) followed by multivariate statistical analysis has been successfully applied to the plasma phospholipids metabolic profiling in type 2 diabetes mellitus (DM-2). Principal components analysis and partial least-squares discriminant analysis (PLS-DA) model...

Subject

Chemistry

Chromatography

Principal component analysis

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