Effect of Recombinant ApoA-I Milano on Coronary Atherosclerosis in Patients With Acute Coronary Syndromes

E. Nissen, Steven; Tsunoda, Taro; Murat Tuzcu, E.; Schoenhagen, Paul; J. Cooper, Christopher; Yasin, Muhammad; M. Eaton, Gregory; A. Lauer, Michael; Scott Sheldon, W.; L. Grines, Cindy; W. Halpern, Stephen; Crowe, Tim; C. Blankenship, James; A. Kerensky, Richard

doi:10.1001/jama.290.17.2292

Public

Effect of Recombinant ApoA-I Milano on Coronary Atherosclerosis in Patients With Acute Coronary Syndromes

Published in JAMA • Nov 4, 2003

Authors:

Steven E. Nissen

Taro Tsunoda

E. Murat Tuzcu

Abstract

CONTEXT: Although low levels of high-density lipoprotein cholesterol (HDL-C) increase risk for coronary disease, no data exist regarding potential benefits of administration of HDL-C or an HDL mimetic. ApoA-I Milano is a variant of apolipoprotein A-I identified in individuals in rural Italy who exhi...

Subject

Medicine

Atheroma

Intravascular ultrasound

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