Immunosuppressive therapy in lupus nephritis: The Euro‐Lupus Nephritis Trial, a randomized trial of low‐dose versus high‐dose intravenous cyclophosphamide

Houssiau, Frédéric; Vasconcelos, Carlos; D’Cruz, David; Domenico Sebastiani, Gian; de Ramón Garrido, Enrique; Giovanna Danieli, Maria; Abramovicz, Daniel; Blockmans, Daniël; Mathieu, Alessandro; Di̇reskeneli̇, Haner; Galeazzi, Mauro; Gül, Ahmet; Levy, Yair; Petera, P; Popović, Rajko; Petrović, Radmila; Alberto Sinico, Renato; Cattaneo, Roberto; Font, Josep; Depresseux, Geneviève; Cosyns, Jean‐Pierre; Cervera, Ricard

doi:10.1002/art.10461

Public

Immunosuppressive therapy in lupus nephritis: The Euro‐Lupus Nephritis Trial, a randomized trial of low‐dose versus high‐dose intravenous cyclophosphamide

Published in Arthritis & Rheumatism • Aug 1, 2002

Authors:

Frédéric Houssiau

Carlos Vasconcelos

David D’Cruz

Abstract

OBJECTIVE: Glomerulonephritis is a severe manifestation of systemic lupus erythematosus (SLE) that is usually treated with an extended course of intravenous (IV) cyclophosphamide (CYC). Given the side effects of this regimen, we evaluated the efficacy and the toxicity of a course of low-dose IV CYC ...

Subject

Medicine

Lupus nephritis

Cyclophosphamide

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