Bortezomib plus Melphalan and Prednisone for Initial Treatment of Multiple Myeloma

F. San Miguel, Jesús; Schlag, Rudolf; K. Khuageva, Nuriet; Α. Dimopoulos, Meletios; Shpilberg, Ofer; Kropff, Martin; Špıčka, Ivan; Teresa Petrucci, Maria; Palumbo, Antonio; Samoilova, Olga; Dmoszyńska, Anna; Km, Abdulkadyrov; Schots, Rik; Jiang, Bin; Mateos, María-Victoria; C. Anderson, Kenneth; Esseltine, Dixie; Liu, Kevin; Cakana, Andrew; van de Velde, Helgi; G. Richardson, Paul

doi:10.1056/nejmoa0801479

Public

Bortezomib plus Melphalan and Prednisone for Initial Treatment of Multiple Myeloma

Published in New England Journal of Medicine • Aug 27, 2008

Authors:

Jesús F. San Miguel

Rudolf Schlag

Nuriet K. Khuageva

Abstract

BACKGROUND: The standard treatment for patients with multiple myeloma who are not candidates for high-dose therapy is melphalan and prednisone. This phase 3 study compared the use of melphalan and prednisone with or without bortezomib in previously untreated patients with multiple myeloma who were i...

Subject

Medicine

Melphalan

Prednisone

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