MicroRNA‐146a contributes to abnormal activation of the type I interferon pathway in human lupus by targeting the key signaling proteins

Tang, Yuanjia; Luo, Xiaobing; Cui, Huijuan; Ni, Xuming; Yuan, Min; Guo, Yanzhi; Huang, Xinfang; Zhou, Haibo; de Vries, Niek; Peter Tak, Paul; Chen, Shunle; Shen, Nan

doi:10.1002/art.24436

Public

MicroRNA‐146a contributes to abnormal activation of the type I interferon pathway in human lupus by targeting the key signaling proteins

Shared by NobleBlocks on Mar 28, 2009 • 12:00 AM UTC

Authors:

Yuanjia Tang

Xiaobing Luo

Huijuan Cui

Abstract

Abstract Objective MicroRNA have recently been identified as regulators that modulate target gene expression and are involved in shaping the immune response. This study was undertaken to investigate the contribution of microRNA‐146a (miR‐146a), which was identified in the pilot expression profiling ...

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