The use of theranostic gadolinium-based nanoprobes to improve radiotherapy efficacy.

L, Sancey; F, Lux; S, Kotb; S, Roux; S, Dufort; A, Bianchi; Y, Crémillieux; P, Fries; JL, Coll; C, Rodriguez-Lafrasse; M, Janier; M, Dutreix; M, Barberi-Heyob; F, Boschetti; F, Denat; C, Louis; E, Porcel; S, Lacombe; Duc G, Le; E, Deutsch; JL, Perfettini; A, Detappe; C, Verry; R, Berbeco; KT, Butterworth; SJ, McMahon; KM, Prise; P, Perriat; O, Tillement

doi:10.1259/bjr.20140134

Public

The use of theranostic gadolinium-based nanoprobes to improve radiotherapy efficacy.

Shared by NobleBlocks on Jul 3, 2014 • 12:00 AM UTC

Authors:

Sancey L

Lux F

Kotb S

Abstract

A new efficient type of gadolinium-based theranostic agent (AGuIX®) has recently been developed for MRI-guided radiotherapy (RT). These new particles consist of a polysiloxane network surrounded by a number of gadolinium chelates, usually 10. Owing to their small size (<5 nm), AGuIX typically exhibi...

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