Chaperone-mediated coupling of endoplasmic reticulum and mitochondrial Ca2+ channels

Szabadkai, György; Bianchi, Katiuscia; Várnai, Péter; De Stefani, Diego; R. Wieckowski, Mariusz; Cavagna, Dario; I. Nagy, Anikó; Balla, Tamás; Rizzuto, Rosario

doi:10.1083/jcb.200608073

Public

Chaperone-mediated coupling of endoplasmic reticulum and mitochondrial Ca2+ channels

Shared by NobleBlocks on Dec 18, 2006 • 12:00 AM UTC

Authors:

György Szabadkai

Katiuscia Bianchi

Péter Várnai

Abstract

The voltage-dependent anion channel (VDAC) of the outer mitochondrial membrane mediates metabolic flow, Ca2+, and cell death signaling between the endoplasmic reticulum (ER) and mitochondrial networks. We demonstrate that VDAC1 is physically linked to the endoplasmic reticulum Ca2+-release channel i...

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!